Actually, games by their very nature are graphically intensive programs. The calls from the CPU to the RAM are not as intensive as you would think. Once loaded, the perfomance of the game relies more on the GPU and video RAM.
I agree that any system will run faster when all it's compnents are optimized (CPU, RAM, GPU, video RAM, Hard Drives, ect.), but if all are optimal except the RAM, the performance loss due to the loss of DDR functionality is minimal. There really is no noticeable difference between running 2x512MB with DDR and 1x1GB.
I was thinking more along the lines of optimizing program code, running some scientific applications, and doing controls programming as RAM instensive applications.