First of all, have you run LiveUpdate to make sure you have the latest Ghost updates?
I personally haven't run into that exact problem, but you may want to consider an alternative backup solution. I use BartPE with the DriveImageXML plugin to do backups to hard drives. BartPE is basically a bootable Windows CD that runs plugins that you add before you burn the boot disc. I've found it to be faster and more reliable for doing clones to hard drive than Ghost. I have a good success rate with burning backup discs with Ghost, but I've encountered more problems when backing up to another hard drive. I'm not sure if it's due to the large size of the file, the formatting on the drive, or what. However, I have used BartPE to successfully clone over 70 gigs of data to a new hard drive in my friend's laptop, so you should be good to go with it. All you need is a blank CD and a Windows disc, plus the software I mentioned above. Here are the links:http://www.nu2.nu/pebuilder/http://www.runtime.org/peb.htm
Download both apps, install BartPE, add the DriveImageXML file as a plugin, insert your Windows disc, and have it create an image. From there, burn it to a CD and reboot to the CD (it will run while Windows is running, but you will get a better copy if you reboot into the CD instead of doing it while Windows is running). Open DriveImageXML and follow the instructions, it's pretty simple. You can also specify what size chunks to break the image into if you're having trouble with a lot of data.