I purchased this Nook Color specifically because I was taking a very long trip to China and wanted to be able to read without carrying a ton of books. I also liked that it had email capability...
This is an awesome mouse with an excellent grip for a mid sized to large size hand. Right-handed, comfortable, trendy, upscale, red, responsive, functional, task oriented.
Overall A+++
Fantastic had this machine 6 months and can honestly say have had no bother with it. Plays games better than most desktops and keeps up with the rest which is outstanding for a...
As long as you have the 32 bit operating system (e.g., Vista, or XP for that matter) then 1 slot can be filled.
If you ever decide to go to a 64 bit operating system you will have to get another RAM module to fill the second slot.
I tried to install Vista Premium 64-bit on my desktop, with a single stick 256 MB RAM module and it failed to install. I ended up getting 2 GB (2 - 1 GB RAM modules) of RAM for this PC.
Whether Vista installs or not is not based on whether you have 1 or 2 slots filled.
The problem that Phogsten had was most likely related to the fact that he was trying to install Vista on only 256MB of RAM. That amount of RAM is anemic on Windows XP... on Vista it's even worse.
So yes, you can have mismatched memory pairs (1GB + 2GB). However, you will lose dual-channel memory mode, and a little bit of overall computer performance because of it.