I am running doom 3 with the omega 4.6 drivers. At medium settings and 1024x768 on my 4750. It hasn't crashed on me yet and I don't get artifacts. Its a little twitchy when walking around but when it comes to zombie shooting it is rather smooth. I wish there was more ammo though, i had to face an imp with a handgun and i got quickly squished. also those zombies seem to appear out of nowhere. and do those flying spectral things can they damage you?