Hmm, I just can't decide on a proper hard drive configuration, so perhaps someone from this forum, or maybe Adam/Luke could give me some help

If I want to have two hard drives, not in RAID (RAID 0 sounds a little risky for school work), and mostly for working with large files (3dsmax, photoshop, illustrator, video editing etc), would two individual 5400rpm SATA drives out-perform two 7200rpm PATA drives?
I think I've read from one of the earlier posts that a 7200rpm PATA drive would be faster for large files, but I guess that's for a single drive setup only? (I'm assuming that performance would decrease when the 2 drives are competing for the same PATA channel?) So, would the 5400 SATA drives perform better in this scenario?