Well, if they're about the same price, it seems that you get much more for you money with the 8103. The better video card might be good for photoshop'ing, and you can always change the resolution settings to a more comfortable level, or even adjust the DPI settings so the resolution is still high but with bigger fonts, so it takes it easy on your eyes
From the "pros"-list of the Asus, only the 2 in the bottom seem to be really an issue, especially if you take seriously the reputedly bad support of Acer (I'm not sure if it's any better with Asus though..never checked it out)
On the other hand, for me the difference on the hard disk size is a big plus on Acer's side (again, considering they're about the same price), since HD space and RAM memory are never too much...there are many apps out there right now that take 1-2Gb on disk, and the tendency is to get worst every day.
Regarding weight, I believe in relative terms it's pretty much equivalent; we can't really "feel" a 13% weight difference. Especially if you think that for this 0.8lb difference you get a much bigger screen, 60% more harddisk space, etc etc. Just get a light case to carry it
I have an Acer 8104 and I wouldn't call the keyboard "ergonomic", it takes much more than that to be ergonomic..I'm not convinced it would make a big difference on the long term. But still, I like the way it looks
IMHO the only pending issue on Acer's side is support, but as I said, I don't know how is it on Asus' side, maybe someone with experience with both companies could tell. If you think 1 year is not much, you can buy their extended support ("Acer Advantage"), to make it 3 years, and may even cover accidental damage. I bought for mine 8104, it's a bargain when you think about the peace of mind you get in return.
I am a newbie on notebooks too, just bought mine, but I hope it was helpful