Update: I lowered the DPI down to 96 from the default of 120 (never thought I'd do that!) and changed the font size to "Large Fonts"... now everything is crisp, sharp, bright -- and easy to read. I'm really impressed with this screen.
Personally I'd recommend using Firefox (instead of IE) and adding this extension:
http://www.cosmicat.com/extensions/textzoom/. It will make reading text on web pages a pleasure. No squinting required, just beautifully sharp text.